어린이와 청소년의 비알콜성음료 섭취에 따른 인공감미료 섭취량 평가

김성단1†․문현경2․이집호1․장민수1․신영1․정선옥1․윤은선1․조한빈1․김정헌1

1서울시보건환경연구원, 2단국대학교 식품영양학과

Assessment of Estimated Daily Intakes of Artificial Sweeteners in Non-alcoholic Beverages for Children and Adolescents

Sung-Dan Kim1 †, Hyun-Kyung Moon2  , Jib-Ho Lee1 , Min-Su Chang1 , Young Shin1 ,

Sun-Ok Jung1 , Eun-Sun Yun1 , Han-Bin Jo1 ,  Jung-Hun Kim1

1 Seoul Metropolitan Government Research Institute of Public Health and Environment, Gyeonggi-do 427-070, Korea

2 Dept. of Food and Nutrition, Dankook University, Gyeonggi-do 448-701, Korea

Running title: 어린이와 청소년의 비알콜성음료 섭취에 따른 인공감미료 섭취량 평가

ABSTRACT

The aims of this study were to estimate daily intakes of artificial sweeteners from beverages and liquid teas and to evaluate their potential health risks for children and adolescents(1 to 19 years old) of Korean. Dietary intake assessment was conducted using the actual level of aspartame, acesulfame-K, and sucralose in non-alcoholic beverages(651 beverages and 87 liquid teas) and the food consumption amount drawn from "The Fourth Korea National Health and Nutrition Examination Survey(2007-2009)". To estimate the dietary intake of non-alcoholic beverage, a total of 6082 children and adolescents(ScenarioⅠ) were compared to 1704 non-alcoholic beverage consumption subjects among them(ScenarioⅡ). The estimated daily intake of artificial sweeteners was calculated based on point estimates and probabilistic estimates. The values of probabilistic artificial sweeteners intakes which is a Monte-Carlo approach considering probabilistic density functions of variables were presented by using the probabilistic model. The level of safety for artificial sweeteners was evaluated by comparisons with acceptable daily intake(ADI) for aspartame(0-40 mg/kg bw/day), acesulfame-K(0-15 mg/kg bw/day), and  sucralose(0-15 mg/kg bw/day) set by the World Health Organization(WHO). For total children and adolescents(scenarioⅠ), mean daily intakes of aspartame, acesulfame-K, and sucralose estimated by probabilistic estimates using Monte Carlo simulation were, respectively, 0.09, 0.01, and 0.04 mg/kg bw/day and 95th percentile daily intakes of those were, respectively, 0.30, 0.02, and 0.13mg/kg bw/day. For consumers-only (scenarioⅡ), mean daily intakes of aspartame, acesulfame-K, and sucralose estimated by probabilistic estimates using Monte Carlo simulation were, respectively, 0.52, 0.03, and 0.22 mg/kg bw/day and 95th percentile daily intakes of those were, respectively, 1.80, 0.12, and 0.75 mg/kg bw/day. For scenario Ⅰ․Ⅱ, None of aspartame, acesulfame-K, and sucralose had a mean and 95th percentile intake that exceeded the 5.06 % of ADI.

KEY WORDS : artificial sweeteners, estimated daily intake, non-alcoholic beverage, probabilistic estimates.